||John O. Mascarenhas, MD, MS
Assistant Professor Medicine, Hematology and Medical Oncology
Mount Sinai School of Medicine
New York, New York
|Dr. John Mascarenhas is a clinical investigator in malignant hematology with a focus in translational research involving the Myeloproliferative Neoplasms. Dr. Mascarenhas is primarily responsible for the clinical trials arm of the Mount Sinai School of Medicine Myeloproliferative Disorders Program headed by Dr. Ronald Hoffman. This program offers phase I/II and III studies for patients with myelofibrosis, polycythemia vera, essential thrombocythemia, chronic myelogenous leukemia, and forms of acute myeloid leukemia. In addition, Dr. Mascarenhas treats patients with myelodysplastic syndrome, hypereosinophilic syndrome, systemic mastocytosis, chronic myelomonocytic leukemia and related issues. He is a member of the American Society of Hematology (ASH).
Medical Degree: New York Medical College, Valhalla, New York
Masters Degree: Biological Sciences, Mount Sinai Graduate School, New York, New York
Residency: Internal Medicine, Brown University, Providence, Rhode Island
Fellowship: Hematology, Mount Sinai Hospital, New York, New York
|Board Certification and Licensure
Medical License: New York
|Clinical and Research Interests
Acute Myelogenous Leukemia-Adult
Chronic Myelocytic Leukemia
1: Mascarenhas J, Hoffman R. A comprehensive review and analysis of the effect of ruxolitinib therapy on the survival of patients with myelofibrosis. Blood. 2013 Apr 9. [Epub ahead of print] PubMed PMID: 23570800.
2: Mascarenhas J, Lu M, Li T, Petersen B, Hochman T, Najfeld V, Goldberg JD, Hoffman R. A phase I study of panobinostat (LBH589) in patients with primary myelofibrosis (PMF) and post-polycythaemia vera/essential thrombocythaemia myelofibrosis (post-PV/ET MF). Br J Haematol. 2013 Apr;161(1):68-75. doi: 10.1111/bjh.12220. Epub 2013 Jan 21. PubMed PMID: 23330839.
3: Lew J, Frucht SJ, Kremyanskaya M, Hoffman R, Mascarenhas J. Hemichorea in a patient with JAK2V617F blood cells. Blood. 2013 Feb 14;121(7):1239-40. doi:
10.1182/blood-2012-12-468751. PubMed PMID: 23411735.
4: Ragupathi L, Najfeld V, Chari A, Petersen B, Jagannath S, Mascarenhas J. A Case Report of Chronic Myelogenous Leukemia in a Patient With Multiple Myeloma and a Review of the Literature. Clin Lymphoma Myeloma Leuk. 2012 Nov 15. doi:pii: S2152-2650(12)00175-9. 10.1016/j.clml.2012.09.010. [Epub ahead of print] PubMed PMID: 23168212.